"It was painful," Baldwin joked to New York magazine at Tuesday night's Tisch on Stage gala in NYC. Aniston, 39, played Baldwin's free-spirited stalker on the Nov. 13 episode.
"I mean, every man who's had to make out with her in TV and movies - I don't know how they do it," he added.
Check out photos of stars kissing.
So does Baldwin - who has a famously contentious relationship with ex Kim Basinger - believe the show's plot that crazy women are better lovers?
"That's assuming I've been with a crazy woman," he said, wagging his finger at the New York magazine reporter. "If I answer that question in the affirmative, that would type a woman I've been with as being crazy, which I really don't feel like doing.
"But I hear it's true - I hear from my friends it's true," he added.
Aniston's appearance earned the show its lowest ratings of the season with only 7.5 million viewers. Oprah's Nov. 6 appearance drew 8 million.
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Steve Martin and Alec Baldwin are co-hosting this year's Academy Awards. Who do you think will be more entertaining?
Alec Baldwin! Have you seen "30 Rock"? Genius!
Neither...I am not the biggest fan of these guys! Bring back Hugh Jackman!
Steve Martin! I have a feeling he'll bring his banjo!
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